🧐An Introduction:
Gut issues are all around, rising within toblooming without- rooting to bad life habits to NSAIDs to junk foods. Reports show that inflammation in the gastric mucosa stay put in 28.2% – 58.6% of patients even after kicking outH.pylori!Vitamin B5 and Vitamin U are found to be the natural barrier plumbers!
💊Vitamin B5 (pantothenic acid):
A water-soluble vitamin, precursor to Coenzyme A(CoA), is one of the metabolic directors.
You get it from: Eggs, liver, seeds, nuts, cabbage, avocado, broccoli, whole grains & even your good gut bugs!
It’s the fuel behind ATP, thanks to its role in making Coenzyme A (CoA), of which, Acyl CoA and Acyl- carrier protein are key fat and carb burners.
😵💫Fun Fact: You make ~40kg of ATP per day!
⚠️ But wait—without its Sodium-dependent multivitamin transporter (SMVT), things go down fast: gut leaks, inflammation, even early death! Also, be cautious to its high intake!
👀Where can we see the use?
💊Dexapanthenol- for skin hydration, recolonization, regeneration of epidermal barrier.
🧬It’s also known to show anticancer effects in melanoma patients.
🥑Gastrointestinal protection from oxidative damage through lipid accumulation and increasing glutathione.
🤓 Also boosts: Mitochondria, mental clarity, detox, wound healing.
💊Vitamin U (S- methylmethionine): Anti-ulcer vitamin
- S-methylmethionine sulfonium chloride (S-methylmethionine, methylmethionine, vitamin U) is a vitamin-like compound.
- You get it from: white cabbage, asparagus, broccoli, fresh potato juice, carrots, celery, beets, parsley, tomatoes, bananas, green tea, raw egg yolks, raw milk, liver.
🛅The mechanism:
- Vitamin B5 produces sufficient ATP to activate SAM(S-adenosylmethionine) levels which are maintained by Vitamin U.
- S-methylmethioninedonates methyl groups for DNA, RNA and protein methylation which directly links to gut cell growth.
- Vitamin U also regulate xenobiotic, glucose and your body clock!
👀 Benefits?
🧬It has great antitumor effect.
🍳It provides armour-like protection to gut by boosting mucosal blood flow, increasing mucin, balancing acid, and stimulating cell growth and repair.
🥦It alleviate intestinal damage under heat stress.
🦠Its also potential in erosive gastrointestinal disorders.
💊🧪Combined Use!
B5 + U = ATP + Mitochondria homeostasis + mucosal protection + anti-inflammatory + antioxidant + regeneration
B5 = Bacterial diversity, Be positive, Biogenesis of mitochondria, Bowel clearance, Biotics-pre, pro, post = fuel
U= unburden your gut = fixer
🤓Youneed to ‘fix(U)’ using the ‘fuel (B5)’ and feel fabulous!
Reference:
Shichkin VP. Vitamin B5 and vitamin U review: justification of combined use for the treatment of mucosa-associated gastrointestinal pathologies. Frontiers in Pharmacology. 2025 May 21;16:1587627.
Link:
Written by Dr Shobhitha Tantry B